Technologies for integrating biological data
Deputy Executive Director of Laboratories for the Institute for Infocomm Research in Singapore. He has done interesting research in several areas: he is known for his theorems on the ‘Bounded Degree Property’ of Nested Relational Calculus and SQL and invented the ‘Kleisli Query System’, which was the first broad-scale data integration system that solved many of the so-called ‘impossible’ bioinformatics integration problems. His most recent interest is in the analysis of emerging patterns of gene expression profiles.
Limsoon Wong, Institute for Infocomm Research 21 Heng Mui Keng Terrace, Singapore 119613 Tel: +65 6874 2099 Fax: +65 6872 5743 E-mail: limsoon{at}lit.or.sg/limsoon{at}izr.a-star.edu.sg
The process of building a new database relevant to some field of study in biomedicine involves transforming, integrating and cleansing multiple data sources, as well as adding new material and annotations. This paper reviews some of the requirements of a general solution to this data integration problem. Several representative technologies and approaches to data integration in biomedicine are surveyed. Then some interesting features that separate the more general dataintegration technologies from the more specialised ones are highlighted.
Keywords: data integration, data model, query language, application programming interface, EnsEMBL, Kleisli
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