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Briefings in Bioinformatics 2004 5(1):39-55; doi:10.1093/bib/5.1.39
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© Henry Stewart Publications

Special Issue papers

Swiss-Prot: Juggling between evolution and stability

Amos Bairoch
Heads the Swiss-Prot group at the SIB and is a professor at the Department of Structural Biology and Bioinformatics of the University of Geneva.

Brigitte Boeckmann
Working in the Swiss-Prot group for 16 years. She has been involved in annotation and tool development and is now coordinating automatic annotation in Swiss-Prot.

Serenella Ferro
Background in biochemistry and chemistry and has worked as a Swiss-Prot head annotator for 15 years.

Elisabeth Gasteiger
coordinates software development in the SIB Swiss-Prot group and is in charge the ExPASy server.


Amos Bairoch, Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1 Rue Michel Servet, 1211 Geneva 4, Switzerland Tel: +41 22 379 50 50 Fax: +41 22 379 58 58 E-mail: swiss-prot{at}expasy.org

We describe some of the aspects of Swiss-Prot that make it unique, explain what are the developments we believe to be necessary for the database to continue to play its role as a focal point of protein knowledge, and provide advice pertinent to the development of high-quality knowledge resources on one aspect or the other of the life sciences.

Keywords: protein sequence, database, functional annotation, automatic annotation, sequence analysis, user feedback


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