Briefings in Bioinformatics Advance Access originally published online on May 4, 2007
Briefings in Bioinformatics 2007 8(6):396-414; doi:10.1093/bib/bbm011
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A practical guide to the art of RNA gene prediction
Corresponding author. Irmtraud M. Meyer, Bioinformatics Centre and Department of Computer Science, University of British Columbia, 2366 Main Mall, Vancouver, BC, Canada V6T 1Z4. Tel: +1-604-8274222; Fax: +1-604-8225485; E-mail: irmtraud.meyer{at}cantab.net
This review introduces the different strategies and computational methods that can be used in order to predict RNA genes. It discusses our current view of RNA genes as well as recent computational analyses of RNA genes and concludes with an outlook to future directions in algorithm development and data analyses.
Keywords: gene prediction, RNA genes, non-coding genes, ncRNA, RNA secondary structure, transcriptomics
Received (in revised form): March 19, 2007.
Accepted: March 20, 2007.
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