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Briefings in Bioinformatics Advance Access originally published online on December 7, 2007
Briefings in Bioinformatics 2008 9(2):166-173; doi:10.1093/bib/bbm061
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© The Author 2007. Published by Oxford University Press. For Permissions, please email: journals.permissions@oxfordjournals.org

The HUPO proteomics standards initiative—easing communication and minimizing data loss in a changing world

Sandra Orchard and Henning Hermjakob

Corresponding author. Sandra Orchard, EMBL – European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK. Tel: +44 (0)1223 494 675; Fax: +44 (0)1223 494 468; E-mail: orchard{at}ebi.ac.uk

The amount of data currently being generated by proteomics laboratories around the world is increasing exponentially, making it ever more critical that scientists are able to exchange, compare and retrieve datasets when re-evaluation of their original conclusions becomes important. Only a fraction of this data is published in the literature and important information is being lost every day as data formats become obsolete. The Human Proteome Organisation Proteomics Standards Initiative (HUPO-PSI) was tasked with the creation of data standards and interchange formats to allow both the exchange and storage of such data irrespective of the hardware and software from which it was generated. This article will provide an update on the work of this group, the creation and implementation of these standards and the standards-compliant data repositories being established as result of their efforts.

Keywords: human proteome organization, proteomics standards initiative, data standardization

Submitted: July 10, 2007. Received (in revised form): November 16, 2007.


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