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Briefings in Bioinformatics Advance Access originally published online on March 9, 2006
Briefings in Bioinformatics 2006 7(2):204-206; doi:10.1093/bib/bbl001
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© The Author 2006. Published by Oxford University Press. For Permissions, please email: journals.permissions@oxfordjournals.org

Book Reviews

Computational Modeling of Genetic and Biochemical Networks.

Edited by James M. Bower and Hamid Bolouri

Computational Molecular Biology, A Bradford Book, The MIT Press, Cambridge, Massachusetts; 2004;

ISBN: 0 262 52423 6; Paperback; 390pp.;

£22.95/$35.00.

The first 150 words of the full text of this article appear below.

‘Computational Modeling of Genetic and Biochemical Networks’ arose from a graduate course taught by the editors in the California Institute of Technology in 1998. The aim of the book is to provide instruction in the application of modelling techniques in molecular and cell biology to graduate students and postdoctoral researchers. It is also intended as a primer in the subject for both theoretical and experimental biologists.

The preface discusses the interplay between experiments, theory and modelling by addressing two important questions: Why is modelling necessary and what type of modelling is appropriate? It also explains the structure and organization of the book, as well as how it should be used. The book is divided into two parts: Modeling Genetic Networks (Chapters 1–5) and Modeling Biochemical Networks (Chapters 6–10). The book concludes with a chapter on multiscale modelling (Chapter 11).

The first part of the book deals with models of gene . . . [Full Text of this Article]

Santiago Schnell
Indiana University School of Informatics and Biocomplexity Institute, Eigenmann Hall 906, 1900 East Tenth Street, Bloomington, Indiana 47406, USA


E-mail: schnell@indiana.edu


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