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Briefings in Bioinformatics Advance Access originally published online on May 4, 2006
Briefings in Bioinformatics 2006 7(2):196-201; doi:10.1093/bib/bbl006
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© The Author 2006. Published by Oxford University Press. For Permissions, please email: journals.permissions@oxfordjournals.org

Abstracts

The first 150 words of the full text of this article appear below.

Briefings in Bioinformatics aims to provide working biologists with an awareness and understanding of the computational approaches available for research and discovery. The Abstracts section of the journal consists of summaries of bioinformatics manuscripts published in the previous quarter. Inclusion of an article in this section indicates that the editors consider it to be among the most interesting and/or useful contributions to the field for the quarter covered. The contents of these reports are briefly distilled for the readers with an emphasis placed on their biological context and potential utility. Publications from the first quarter of 2006 (January–March) are reviewed here.

Genome-wide identification of human functional DNA using a neutral indel model
Gerton Lunter, Chris P. Ponting and Jotun Hein PLoS Computational Biology (2006) Vol. 2, no. 1, p. e5
The vast majority of human genomic sequence is not protein coding, and putative functional roles for almost all of this sequence have yet to be discovered. In light of this knowledge gap, there is a sustained effort underway to develop computational approaches to aid in functional predictions for non-coding . . . [Full Text of this Article]

Stable evolutionary signal in a Yeast protein interaction network
Stefan Wuchty, Albert-Laszlo Barabási and Michael T. Ferdi BMC Evolutionary Biology (2006) Vol. 6, no.1, p. 8
Nonrandom divergence of gene expression following gene and genome duplications in the flowering plant Arabidopsis thaliana
Tineke Casneuf, Stefanie De Bodt, Jeroen Raes, Steven Maere and Yves Van de Peer Genome Biology (2006) Vol. 7, no. 2, p. R13
Transposon-free regions in mammalian genomes
Cas Simons, Michael Pheasant, Igor V. Makunin and John S. Mattick Genome Research (2006) Vol. 16, no. 2, pp. 164–172
Evolution of alternative splicing after gene duplication
Zhixi Su, Jianmin Wang, Jun Yu, Xiaoqiu Huang and Xun Gu Genome Research (2006) Vol. 16, no. 2, pp. 182–189
A genome-wide study of dual coding regions in human alternatively spliced genes
Han Liang and Laura F. Landweber Genome Research (2006) Vol. 16, no. 2, pp. 190–196
"Genome design" model: Evidence from conserved intronic sequence in human–mouse comparison
Alexander E. Vinogradov Genome Research (2006) Vol. 16, no. 3, pp. 347–354
Toward automatic reconstruction of a highly resolved tree of life
Francesca D. Ciccarelli, Tobias Doerks, Christian von Mering, Christopher J. Creevey, Berend Snel and Peer Bork Science (2006) Vol. 311, no. 5765, pp. 1283–1287
A third approach to gene prediction suggests thousands of additional human transcribed regions
Gustavo Glusman, Shizhen Qin, M. Raafat El-Gewely, Andrew F. Siegel, Jared C. Roach, Leroy Hood and Arian F. A. Smit PLoS Computational Biology (2006) Vol. 2, no. 3, p. e18
Gene losses during human origins
Xiaoxia Wang, Wendy E. Grus and Jianzhi Zhang PLoS Biology (2006) Vol. 4, no. 3, p. e52
I. King Jordan

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