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Briefings in Bioinformatics Advance Access originally published online on September 2, 2006
Briefings in Bioinformatics 2007 8(1):2-5; doi:10.1093/bib/bbl030
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© The Author 2006. Published by Oxford University Press. For Permissions, please email: journals.permissions@oxfordjournals.org

HCOP: a searchable database of human orthology predictions

Tina A. Eyre, Mathew W. Wright, Michael J. Lush and Elspeth A. Bruford

Corresponding author. Elspeth A. Bruford, HUGO Gene Nomenclature Committee (HGNC), Department of Biology, University College London, Wolfson House, 4 Stephenson Way, London, NW1 2HE. Tel: 0207 679 7410; Fax: +44 20 7387 3496; E-mail: nome{at}galton.ucl.ac.uk.

The HUGO Gene Nomenclature Committee (HGNC) Comparison of Orthology Predictions (HCOP) search tool combines the human, mouse, rat and chicken orthology assertions made by PhIGs, HomoloGene, Ensembl, Inparanoid, Mouse Genome Informatics (MGI) and HGNC, enabling users to identify predicted ortholog pairs for a specified gene or genes. The HCOP resource provides a useful method to integrate, compare and access a variety of disparate sources of human orthology data.

The HCOP search tool, data and documentation are available at http://www.gene.ucl.ac.uk/hcop.

Keywords: orthology, nomenclature, database, comparative, genes


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