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Abstracts
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Briefings in Bioinformatics aims to provide working biologists with an awareness and understanding of the computational approaches available for research and discovery. The Abstracts section of the journal consists of summaries of bioinformatics manuscripts published in the preceding two months. Inclusion of an article in this section indicates that the editors consider it to be among the most interesting and/or useful contributions to the field for the quarter covered. The contents of these reports are briefly distilled for the readers with an emphasis placed on their biological context and potential utility. Publications from October and November 2006 are reviewed here.
Large-scale turnover of functional transcription factor binding sites in Drosophila
Alan M. Moses, Daniel A. Pollard, David A. Nix, Venky N. Iyer, Xiao-Yong Li, Mark D. Biggin and Michael B. Eisen
PLoS Computational Biology (2008) Vol. 2, no. 10, p. e130
The importance of changes in gene regulation for organismic evolution—as opposed to changes in gene coding sequences per se
Co-evolution of transcriptional and post-translational cell-cycle regulation
Long intervals of stasis punctuated by bursts of positive selection in the seasonal evolution of influenza A virus
Accelerated evolution of conserved non-coding sequences in humans
Forces Shaping the Fastest Evolving Regions in the Human Genome
Large punctuational contribution of speciation to evolutionary divergence at the molecular level