Skip Navigation



Briefings in Bioinformatics Advance Access published online on February 3, 2006
Briefings in Bioinformatics, doi:10.1093/bib/bbk004
This Article
Right arrow Full Text (Rapid PDF)
Right arrow All Versions of this Article:
7/1/48    most recent
bbk004v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Abnizova, I.
Right arrow Articles by Gilks, W. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Abnizova, I.
Right arrow Articles by Gilks, W. R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press. For Permissions, please email: journals.permissions@oxfordjournals.org
Received May 23, 2005
Accepted October 12, 2005

Original Article

Studying Statistical Properties of Regulatory DNA Sequences, and their use in Predicting Regulatory Regions in the Eukaryotic Genomes

Irina Abnizova * and Walter R. Gilks

* To whom correspondence should be addressed.
Irina Abnizova, E-mail: irina.abnizova{at}mrc-bsu.cam.ac.uk


  Abstract

There are no well-known properties in regulatory DNA analogous to those in coding sequences; their spatial location is not regular, the consensus regulatory elements are often degenerate and there are no understandable rules governing their evolution. This makes it difficult to recognize regulatory regions within genome. We review developments in the statistical characterization of regulatory regions and methods of their recognition in eukaryotic genomes.

Keywords: Regulatory regions; Statistical methods; Transcription factor binding sites.

Irina Abnizova is a Research Scientist in MRC Biostatistics Unit. Her current research interests are the development of computational statistics and software focusing on regulatory regions and elements.

Walter Gilks is Programme Leader at MRC Biostatistics Unit. His interests are in the development of statistical methods for the analysis of genomic data.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.