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Briefings in Bioinformatics Advance Access published online on July 18, 2007
Briefings in Bioinformatics, doi:10.1093/bib/bbm035
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© The Author 2007. Published by Oxford University Press. For Permissions, please email: journals.permissions@oxfordjournals.org

Statistical software for gene mapping by admixture linkage disequilibrium

Giovanni Montana and Clive Hoggart

Corresponding author. Giovanni Montana, Imperial College London, Department of Mathematics, South Kensington Campus, 180 Queen's Gate, London SW7 2AZ. Tel: +44 (0) 207-594-8577; E-mail: g.montana{at}imperial.ac.uk

Admixture mapping is a statistical methodology that detects genetic variants in recently admixed populations that are responsible for ethnic differences in disease risk. Three software packages are now available for admixture mapping and we provide a brief overview of the statistical methods and other principal features they implement.

Keywords: gene mapping, admixture linkage disequilibrium, hidden Markov models

Received (in revised form): June 7, 2007.


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